MDC CV - IMT Unadjusted Baseline 1991-1994
2022-09-26
Contents
Common carotid intima-media thickness (IMT) and carotid plaque data obtained from B-mode ultrasonography examination of the right carotid artery using an Acuson 128 CT system (Mountain View, CA, USA) with a 7-MHz transducer. Original (unadjusted) IMT baseline values.
Lines: 6 103
Variables: 19
Selection
Cardiovascular (CV) cohort of MDC. Every other individual in the MDC cohort screened between 1991 to 1994 was invited to a CV project, 6 103 individuals accepted the invitation.
Reference
Hedblad B, Nilsson P, Janzon L, Berglund G. Relation between insulin resistance and carotid intima-media thickness and stenosis in non-diabetic subjects. Results from a cross-sectional study in Malmö, Sweden. Diabet Med. 2000;17(4):299-307.
Rosvall M, Janzon L, Berglund G, Engström G, Hedblad B. Incident coronary events and case fatality in relation to common carotid intima-media thickness. J Intern Med. 2005;257(5):430-7.
List of variables
Unadjusted original IMT-variables from MDC baseline 1991-1994
| Name | Variable label | Type | Format | Value label | Male | Female |
|---|---|---|---|---|---|---|
| lopnrMKC | Sequence number for baseline examination in the MDC cohort (Numeric) | Numeric | F5 | 2572 | 3531 | |
| lopnr_ul | Sequence number for ultrasound examination in MDC-CV cohort (also named patnr_ul) | Numeric | F5 | 2572 | 3531 | |
| u_dat | Date of carotid ultrasound baseline examination. Remarks: The variable u_dat equals date0 (see data with adjusted IMT-variables) for all individuals except for two, lopnrMKC=28996 and lopnrMKC=40313. These two individuals were examined twice at baseline, results from the first examination was used for the unadjusted IMT-variables (u_dat to plack6), but data from the second examination (with date equal to sdate in Bodycomp) was used for the adjusted IMT-variables (date0 to aplqsc_0, see separate data file). About 98% of the individuals in MDC-CV have identical dates for u_dat and start_d (the latter is MDC baseline screening date, which is derived from sdate in Bodycomp and DATUM in Cellcounter). | Date | SDATE10 | 2572 | 3531 | |
| stenos | Carotid stenos at baseline examination (% lumenreduction at plaques) | Numeric | F2 | 2234 | 3043 | |
| lumendia | Lumendiameter in the common carotid artery at baseline examination (mm) | Numeric | F5.2 | 2471 | 3448 | |
| imtmin | Minimum intima-media-thickness in the common carotid artery at baseline examination (mm) | Numeric | F4.2 | 2547 | 3510 | |
| imtmedel | Mean intima-media-thickness (unadjusted) in the common carotid artery at baseline examination (mm). Remarks: The variable imtmedel equals the unadjusted imtcca0 value (i e without subtraction of the term 0,026) (see data with adjusted IMT-variables) for all individuals except for two individuals (see the variable descriptions for u_dat for further explanation of these two individuals). | Numeric | F4.2 | 2547 | 3510 | |
| imtmax | Maximal intima-media-thickness in the common carotid artery at baseline examination (mm) | Numeric | F4.2 | 2547 | 3510 | |
| imt_bmax | Maximal intima-media-thickness (unadjusted) in the carotid bifurcation at baseline examination (mm). Remarks: The variable imt_bmax equals the unadjusted imtbulb0 value (i e without subtraction of the term 0,042) (see data with adjusted IMT-variables) for all individuals except for two individuals (see the variable descriptions for u_dat for further explanation of these two individuals). | Numeric | F4.2 | 1790 | 2357 | |
| plq3 | Plaque score (3-point scale) at baseline examination. Remarks: Only available for lopnr_ul=1- 1679 (until 19920531). The variable plq3 equals the plqsc3_0 value (see data with adjusted IMT-variables) for all individuals except for two, lopnrMKC=40313 (see the variable description for u_dat for further explanation of this individual) and lopnrMKC=43731 (reason for discrepancy is unclear). | Numeric | F1 | 0 = no plaque 1 = one plaque 2 = two or more plaques -9 = missing (no result available) | 588 | 1012 |
| plq6 | Plaque score (6-point scale) at baseline examination. Remarks: Only available for lopnr_ul=1680-6117 (from 19920601). The variable plq6 equals the plqsc6_0 value for all individuals except for one, lopnrMKC=40313 (see the variable description for u_dat for further explanation of this individual). | Numeric | F1 | 0 = no plaque or wall thickening 1 = one small plaque (<10 mm2) or one wall thickening (>1,2 mm) 2 = two or more small plaques (<10 mm2) or wall thickenings (>1,2 mm) 3 = one plaque >=10 mm2 4 = one plaque >=10 mm2 and one or more small plaques or wall thickenings 5 = two or more plaques >=10 mm2, and/or one circumferent plaque and/or one large plaque with >50 % stenosis -9 = missing, no result available | 1867 | 2382 |
| sten | Classes of stenosis (derived from the variable 'stenos'). | Numeric | F1 | 0 = no stenos 1 = stenos 5-29% 2 = stenos >29% | 2234 | 3043 |
| imt_m | Quintiles of the variable 'imtmedel' (men). | Numeric | F1 | 1 = lo-0.659 mm 2 = 0.660-0.729 mm 3 = 0.730-0.809 mm 4 = 0.810-0.909 mm 5 = 0.910-hi mm | 2270 | 0 |
| imtb_m | Quintiles of the variable 'imt_bmax' (men). | Numeric | F1 | 1 = lo-1.011 mm 2 = 1.012-1.229 mm 3 = 1.230-1.509 mm 4 = 1.510-1.999 mm 5 = 2.000-hi mm | 1590 | 0 |
| imt_k | Quintiles of the variable 'imtmedel' (women). | Numeric | F1 | 1 = lo-0.639 mm 2 = 0.640-0.699 mm 3 = 0.700-0.759 mm 4 = 0.760-0.839 mm 5 = 0.840-hi mm | 0 | 3224 |
| imtb_k | Quintiles of the variable 'imt_bmax' (women). | Numeric | F1 | 1 = lo-0.959 mm 2 = 0.960-1.129 mm 3 = 1.130-1.349 mm 4 = 1.350-1.749 mm 5 = 1.750-hi mm | 0 | 2161 |
| plaque | Presence of carotid plaque (derived from the variables 'plq3' and 'plq6'). | Numeric | F1 | 0 = no 1 = yes (plq3>=1 or plq6>=2) | 2455 | 3394 |
| plack6 | Presence of plaque determined using the 6-point scale (derived from the variable 'plq6'). | Numeric | F1 | 0 = no 1 = yes (plq6>=2) | 1867 | 2382 |
| hr | Heart rate at ultrasound baseline examination (beats per minute). Remarks: Only available for lopnr_ul=1690-6117. | Numeric | F3 | 1921 | 2436 |